BIOMEDICAL ENGINEERING AND PROTEOMICS

Biomedical Applications of Proteomics

Background. Most tumor-associated antigens (TAA) currently used for immunotherapy of cancer are also expressed in normal tissues, which may induce tolerance and impair T cell-mediated immunity. However, there is limited information about how physiological expression in normal tissues alters the function of TAA-specific T cells. Methodology/Principal Findings. We used a T cell receptor transgeni...

Synthesis and optimization of Chitosan nanoparticles: Potential applications in nanomedicine and biomedical engineering

Background: Chitosan nanoparticles have become of great interest for nanomedicine, biomedical engineering and development of new therapeutic drug release systems with improved bioavailability, increased specificity and sensitivity, and reduced pharmacological toxicity. The aim of the present study is to synthesis and optimization of chitosan nanoparticles for industrial and biomedical applicati...

Medical Physics and Biomedical Engineering

Proteomics – A New Approach in Biomedical Studies

The field of clinical proteomics has rapidly evolved during the past few years and is continuously growing as new methodologies and technologies emerge. The focus of this article is to present a short introduction into the field of proteome analysis as well as its applications to human disease biomarker discovery. Human body contains approximately 1 million of proteins that are products of over...

Polymers for Biomedical Engineering